[The influence of exercises on rehabilitation and reconditioning tables on the selected parameters of fat and carbohydrate management]. / Wplyw treningu na stolach rehabilitacyjno-rekondycyjnych na wybrane parametry gospodarki tluszczowo-weglowodanowej.

UNLABELLED: The results of numerous studies have recently revealed that the motor activity are able to prolong the live of middle-aged and elderly human subjects preventing serious diseases and premature death. A regular physical activity decreases the number of fat cells and increases their vulnerability to insulin. Physical exercises regulate the metabolic disorders observed in obesity. The physical activity of persons with lipid disorders may induce some favorable changes and an increase the HDL of cholesterol fraction. The influence of physical activity on fat and carbohydrate changes was confirmed in some studies. The aim of the study was to evaluate the selected parameters of the fat and carbohydrate changes in subjects after 15 days health-related training performed on rehabilitation and reconditioning tables SLENDER-LIFE. MATERIAL AND METHODS: A group of 50 patients during health-resort therapy were examined on the first and last day of training for biochemical blood parameters. RESULTS: The examined biochemical parameters were reduced statistically significantly in all subjects, as follows: the total cholesterol concentration, the LDL value fraction of cholesterol, triglycerides, and the glucose concentration. CONCLUSIONS: It has been documented that the level of the HDL fraction of cholesterol and the basic energy index were increased in the examined subjects. The training on the rehabilitation and reconditioning tables has been confirmed by the subjects as useful and efficient.

[Effect of fluvastatin and fenofibrate on reactive oxygen species generation and lipid peroxidation in patients with dyslipidemia]. / Wplyw fluwastatyny i fenofibratu na wytwarzanie reaktywnych form tlenu i peroksydacje lipidów u chorych z dyslipidemia.

The effect of fluvastatin and fenofibrate on O2-generation by neutrophils and MDA concentration in mixed hyperlipidaemic patients with stable angina was studied. Thirty-five patients (13 men and 22 women aged 40-77 years) were randomly divided into two groups. Group I comprised 20 patients who were administered fluvastatin 40 mg once daily at bedtime for 30 days. Group II consisted of 15 patients who were administered fenofibrate 200 mg once daily at bedtime for 30 days. The control group comprised 11 clinically healthy persons, aged 21-54 years. Neutrophil O2-generation was measured using Bellavite et al. method and MDA concentrations in plasma and erythrocytes were determined by Placer et al. method. It was shown that fluvastatin had no significant effect on O2-generation while fenofibrate increased its generation. None of the examined drugs caused changes of MDA concentrations in plasma and erythrocytes.

[Effect of fluvastatin and fenofibrate on the antioxidative barrier enzyme activity in patients with dyslipidemia]. / Wplyw fluwastatyny i fenofibratu na aktywnosc enzymów bariery antyoksydacyjnej u chorych z dyslipidemia.

The effect of fluvastatin and fenofibrate on antioxidative enzymatic activity in patients with stable angina and mixed hyperlipidaemia was investigated. Thirty-five patients (13 men and 22 women) aged 40-77 years, were randomly divided into two groups. The first group comprised 20 patients who were administered fluvastatin 40 mg once daily at bedtime for 30 days. The second group consisted of 15 patients who were administered fenofibrate 200 mg once daily at bedtime for 30 days. The control group comprised 11 clinically healthy persons aged 21-54 years. The activities of SOD-1, CAT and GSH-Px in erythrocytes were measured. Fluvastatin induced an increase of the activities of all investigated enzymes. Fenofibrate caused no change of enzyme activities in patients with dyslipidaemia.